Investigation of glycopyrrolate as a premedicant drug.
نویسندگان
چکیده
The clinical efficacy of glycopyrrolate, a synthetic anticholinergic drug, for premedication was compared in a double-blind study with that of atropine or hyoscine in patients anaesthetized with diethyl ether. The antisialogogue actions of the three drugs were similar. Glycopyrrolate produced less tachycardia, pyrexia and blurred vision than atropine, and its sedative effect was less than that of hyoscine.
منابع مشابه
192 British Journal of Anaesthesia
McCubbin, T. D., Brown, J. H., Dewar, K. M. S., Jones, C. J., and Spence, A. A. (1979). Glycopyrrolate as a premedicant: comparison with atropine. Br. J. Anaesth., 51, 885. Rupreht, J. (1980). Physostigmine rcversaj of diazepam. Anesthesiology, (in press). Dworacek, B. (1976). Central anticholinergic syndrome in anaesthetic practice. Acta Anaesthesiol. Belg., 27, 45. Selenati, A. (1979). Recett...
متن کاملBritish Journal of Anaesthesia Leeds Dosage of Ici 35 868
McCubbin, T. D., Brown, J. H., Dewar, K. M. S., Jones, C. J., and Spence, A. A. (1979). Glycopyrrolate as a premedicant: comparison with atropine. Br. J. Anaesth., 51, 885. Rupreht, J. (1980). Physostigmine rcversaj of diazepam. Anesthesiology, (in press). Dworacek, B. (1976). Central anticholinergic syndrome in anaesthetic practice. Acta Anaesthesiol. Belg., 27, 45. Selenati, A. (1979). Recett...
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OBJECTIVE To evaluate the effects of hydromorphone, hydromorphone and glycopyrrolate, medetomidine, and butorphanol premedication on the difficulty and time required to pass an endoscope into the stomach and duodenum of cats anesthetized with ketamine and isoflurane. DESIGN Randomized complete block crossover study. ANIMALS 8 purpose-bred adult female cats. PROCEDURES Each cat was premedi...
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Glycopyrrolate, a quaternary ammonium anticholinergic compound is a potentially useful bronchodilator. To determine the efficacy, optimal dose, and duration of action of inhaled glycopyrrolate, we gave the drug to 11 asthmatic patients. Each subject received placebo or glycopyrrolate (100, 200, 600, or 1,200 micrograms) by inhalation in a double-blind, randomized, crossover design. Measurements...
متن کاملEquine piroplasmosis treatment protocols: specific effect on orocaecal transit time as measured by the lactose 13C-ureide breath test.
REASONS FOR PERFORMING STUDY Imidocarb dipropionate is the drug of choice for equine piroplasmosis but its administration causes severe colic and diarrhoea. An imidocarb protocol that reduces these effects is needed. OBJECTIVES 1) Quantification of the effects of imidocarb dipropionate on equine orocaecal transit time (OCTT), with and without atropine or glycopyrrolate premedication and 2) in...
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عنوان ژورنال:
- British journal of anaesthesia
دوره 52 5 شماره
صفحات -
تاریخ انتشار 1980